Description

Lappaconine is a diterpenoid alkaloid derived from specific Aconitum species, valued for its complex molecular structure and significant biological activity. This compound serves as a crucial reference standard and a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on neuropharmacology, analgesic studies, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for quality control and analytical method development in drug discovery and manufacturing.
• Neuroscience Research: Investigated for its effects on ion channels and neuronal signaling pathways, supporting studies in neuropathic pain and neurological disorders.
• Medicinal Chemistry Intermediate: Serves as a sophisticated building block for the semi-synthesis of novel alkaloid derivatives with potential therapeutic applications.
• Analytical Testing: Employed in HPLC, LC-MS, and NMR analyses for the identification and quantification of related alkaloids in plant extracts and finished products.
• Biochemical Assays: Used in vitro to study receptor binding affinity and enzymatic interactions relevant to pharmacological activity.

Basic Information

Product Name	Lappaconine
CAS No.	23943-93-3
Molecular Formula	C32H44N2O8
Molecular Weight	584.71 g/mol
Synonyms	Lappaconitine Impurity; (1α,14α,16β)-20-Ethyl-1,14,16-trimethoxyaconitane-4,8,9-triol 4,8-Diacetate 9-Benzoate; Lappaconitine Related Compound; Aconitum Alkaloid; N-Deacetyllappaconitine; Contact for additional synonyms
EINECS	Contact for details

Quality Control

Our Lappaconine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant standards for fine chemicals and can support compliance needs for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.