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5Beta-Cholan-3Alpha,7Alpha,24-Triol CAS NO 23848-46-6


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CAS No.:23848-46-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5Beta-Cholan-3Alpha,7Alpha,24-Triol is a high-purity, synthetic bile acid derivative with significant biochemical relevance. This compound serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on metabolic pathways, liver function studies, and the synthesis of novel therapeutic agents.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of more complex bile acid analogs and steroidal drugs.
  • Biochemical Research: Used as a reference standard and probe in studies of bile acid metabolism, cholestasis, and liver physiology.
  • Metabolic Pathway Analysis: Employed in enzymatic assays and in vitro studies to investigate specific metabolic conversions.
  • Analytical Standard: Serves as a high-purity calibration standard for analytical methods such as HPLC, LC-MS, and GC-MS in quality control and research laboratories.
  • Cell Culture & In Vitro Studies: Applied in cell-based assays to study the effects of bile acid derivatives on cellular function and signaling.

Basic Information

Product Name 5Beta-Cholan-3Alpha,7Alpha,24-Triol
CAS No. 23848-46-6
Molecular Formula C24H42O3
Molecular Weight 378.59 g/mol
Synonyms 3α,7α,24-Trihydroxy-5β-cholane; 5β-Cholane-3α,7α,24-triol; (3α,5β,7α)-3,7,24-Trihydroxycholane; 24-Hydroxycholic acid derivative; 3α,7α,24-Trihydroxy-5β-cholan-24-oic acid (parent acid form); Tetrahydroxylated bile acid intermediate
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Quality Control

Our 5Beta-Cholan-3Alpha,7Alpha,24-Triol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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