Description

(R)-(-)-2,2-Dimethyl-1,3-Dioxolan-4-Ylmethyl p-Toluenesulfonate is a high-value chiral building block and key intermediate in organic synthesis. This compound matters for its role in the stereoselective construction of complex molecules, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A critical precursor for the preparation of enantiomerically pure drugs, particularly in nucleoside and carbohydrate chemistry.
• Agrochemical Active Ingredient Development: Used in the research and production of chiral pesticides and herbicides.
• Asymmetric Synthesis Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts.
• Fine Chemical and Specialty Material Production: Employed in the manufacture of advanced materials, liquid crystals, and performance chemicals where specific chirality is required.
• Academic and Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	(R)-(-)-2,2-Dimethyl-1,3-Dioxolan-4-Ylmethyl p-Toluenesulfonate
CAS No.	23788-74-1
Molecular Formula	C13H18O5S
Molecular Weight	286.34 g/mol
Synonyms	(R)-(-)-1,2-Isopropylidene Glycerol 3-Tosylate; (R)-(-)-1,2-O-Isopropylidene Glycerol 3-Tosylate; (R)-1,2-O-Isopropylidene-3-O-tosylglycerol; (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Tosylate; (R)-(-)-1,2-O-Isopropylidene-3-O-(p-toluenesulfonyl)glycerol; (R)-(-)-1,2-O-Cyclohexylidene Glycerol 3-Tosylate (common misnomer); (R)-Glycerol Acetonide Tosylate; (R)-(-)-3-O-Tosyl-1,2-O-isopropylideneglycerol
EINECS	Contact for details

Quality Control

Our (R)-(-)-2,2-Dimethyl-1,3-Dioxolan-4-Ylmethyl p-Toluenesulfonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.