Description

3-Butynyl p-Toluenesulfonate is a versatile organic building block and electrophilic reagent used in advanced chemical synthesis. Its value lies in its ability to introduce a terminal alkyne functional group protected by a tosylate leaving group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those requiring alkyne moieties for click chemistry or further functionalization.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific alkyne-containing structures are required for biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Sonogashira) and nucleophilic substitution reactions to build complex carbon frameworks.
• Bioconjugation Chemistry: Useful for labeling biomolecules or modifying surfaces in diagnostic and biotech applications via alkyne-azide cycloaddition.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands and organometallic catalysts used in homogeneous catalysis.

Basic Information

Product Name	3-Butynyl p-Toluenesulfonate
CAS No.	23418-85-1
Molecular Formula	C11H12O3S
Molecular Weight	224.28 g/mol
Synonyms	3-Butyn-1-yl 4-methylbenzenesulfonate; 4-Methylbenzenesulfonic Acid 3-Butyn-1-yl Ester; p-Toluenesulfonic Acid 3-Butynyl Ester; 1-Butyn-4-yl Tosylate; 3-Butynyl Tosylate; 4-Toluenesulfonic Acid 3-Butynyl Ester; (3-Butynyloxy)toluene-4-sulfonate
EINECS	Contact for details

Quality Control

Our 3-Butynyl p-Toluenesulfonate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.