Description

2'-Deoxyguanylyl-(3'-5')-2'-Deoxycytidine is a defined dinucleotide, a fundamental building block in nucleic acid research and synthesis. This compound is critical for studying DNA structure, function, and enzymatic processes, providing researchers with a high-purity, sequence-specific tool. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in oligonucleotide synthesis, molecular biology, and therapeutic development.

Application

• Oligonucleotide Synthesis: Serves as a key phosphoramidite or solid-phase synthesis intermediate for constructing specific DNA sequences.
• Biochemical Research: Used as a substrate or standard in enzymatic studies involving DNA polymerases, ligases, and nucleases.
• Molecular Biology Probes: A component in the design and fabrication of labeled probes for hybridization assays (e.g., PCR, qPCR, sequencing).
• Therapeutic Development: Acts as a raw material in the research and production of antisense oligonucleotides, siRNA, and other nucleic acid-based therapeutics.
• Analytical Standards: Provides a high-purity reference standard for HPLC, LC-MS, or other analytical method development and quality control.
• Structural Studies: Employed in X-ray crystallography or NMR spectroscopy to investigate DNA duplex formation and stability.

Basic Information

Product Name	2'-Deoxyguanylyl-(3'-5')-2'-Deoxycytidine
CAS No.	23405-83-6
Molecular Formula	C19H25N9O10P
Molecular Weight	570.43 g/mol
Synonyms	d(GpC); Deoxyguanylyl-deoxycytidine; dGpdC; Guanylyl(3'→5')cytidine deoxy dinucleotide; 2'-Deoxyguanylyl-(3'→5')-2'-deoxycytidine; dG-dC; GpC dinucleotide (deoxy); pdGpC
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanylyl-(3'-5')-2'-Deoxycytidine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically assessed via HPLC, UV-Vis spectroscopy, and mass spectrometry. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may lead to degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Extinction Coefficient	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.