Description

n-Acetylneuraminic Acid Methyl Ester is a key methylated derivative of sialic acid, a crucial carbohydrate moiety in glycobiology. This compound is essential for research and synthesis in the life sciences, serving as a vital building block and analytical standard. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic industries for the study and development of glycoconjugates, vaccines, and therapeutic agents.

Application

• Glycobiology Research: A fundamental intermediate for studying sialic acid metabolism, cell surface recognition, and signaling pathways.
• Pharmaceutical Synthesis: Used as a key precursor in the chemical and enzymatic synthesis of sialylated glycoproteins, glycolipids, and complex carbohydrates for therapeutic applications.
• Diagnostic Reagent Production: Serves as a standard or raw material in manufacturing diagnostic kits for detecting enzymes like neuraminidases (sialidases) or specific carbohydrate antigens.
• Vaccine Development: Employed in research for designing conjugate vaccines and understanding host-pathogen interactions involving sialic acid receptors.
• Biochemical Tool: Utilized in enzymatic assays and as a substrate to study the activity and inhibition of sialyltransferases and other glycosyltransferases.
• Standards and References: Acts as a high-purity chromatographic or spectroscopic standard for quality control and analytical method development.

Basic Information

Product Name	n-Acetylneuraminic Acid Methyl Ester
CAS No.	22900-11-4
Molecular Formula	C12H21NO9
Molecular Weight	323.30 g/mol
Synonyms	5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic Acid Methyl Ester; Methyl 5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosidonic Acid; Methyl N-Acetylneuraminate; Methyl Sialate; NANA Methyl Ester; Sialic Acid Methyl Ester; Neu5Ac Methyl Ester
EINECS	Contact for details

Quality Control

Our n-Acetylneuraminic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.