Description

6-Bromo-2-Naphthyl-β-D-Glucuronide is a specialized biochemical reagent primarily used as a chromogenic substrate for enzymatic detection. This compound matters for its high specificity in hydrolytic assays, enabling precise measurement of β-glucuronidase activity. It is needed by research institutions and diagnostic manufacturers developing sensitive assays for microbiology, cell biology, and clinical diagnostics.

Application

• Enzymatic Substrate for β-Glucuronidase: A critical chromogenic reagent in biochemical assays to detect and quantify β-glucuronidase enzyme activity.
• Microbiological Testing: Used in culture media and diagnostic kits for the identification of specific bacterial strains, such as E. coli, which express the GUS reporter gene.
• Molecular & Cell Biology Research: Serves as a key substrate in reporter gene assays (GUS assays) for studying gene expression and promoter activity in plant and mammalian cell research.
• Diagnostic Kit Manufacturing: An essential raw material for producing in-vitro diagnostic (IVD) kits and reagents used in clinical laboratories.
• Pharmaceutical R&D: Employed in drug discovery and development for screening enzyme inhibitors and studying drug metabolism pathways involving glucuronidation.
• Quality Control in Biotechnology: Used as a standard or reference compound in the quality control of enzymes and related biochemical products.

Basic Information

Product Name	6-Bromo-2-Naphthyl-β-D-Glucuronide
CAS No.	22720-35-0
Molecular Formula	C₁₆H₁₅BrO₇
Molecular Weight	399.19 g/mol
Synonyms	6-Bromo-2-naphthyl β-D-glucopyranosiduronic acid; 6-Br-2-Nap-β-GlcU; BNG; 6-Bromo-2-naphthyl-β-D-glucuronide; β-D-Glucopyranosiduronic acid, 6-bromo-2-naphthyl ester; 6-Bromo-2-naphthol β-D-glucuronide; GUS Substrate (6-Bromo-2-naphthyl); 6-Br-β-D-Glucuronide (2-Naphthyl).
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Naphthyl-β-D-Glucuronide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Solubility	Clear, colorless solution in DMSO or DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.