Description

1-Linoleoyl-2-Hydroxy-Sn-Glycero-3-Phosphorylcholine is a specialized lysophospholipid, specifically a lysophosphatidylcholine (LPC) with a linoleoyl fatty acid chain. This compound is a critical biochemical intermediate and signaling molecule, valued for its role in cellular membrane dynamics and metabolic pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced lipidomics sectors, particularly for studies in inflammation, cell signaling, and as a precursor for synthesizing more complex phospholipids.

Application

• Biomedical Research: Used as a key reagent in lipidomics, cell biology, and signal transduction studies to investigate the role of lysophosphatidylcholines in inflammation, apoptosis, and metabolic disorders.
• Pharmaceutical Development: Serves as a critical intermediate or reference standard in the synthesis and quality control of lipid-based drug formulations and active pharmaceutical ingredients (APIs).
• Liposome & Drug Delivery Systems: Employed as a component in the formulation of liposomes and other nanocarriers to modulate membrane fluidity and enhance drug encapsulation efficiency.
• Biochemical Assays: Acts as a substrate or standard in enzymatic assays (e.g., for phospholipase A2 activity) and in calibrating analytical instruments like LC-MS.
• Cosmeceutical Research: Investigated for its potential bioactive properties in skin barrier function and topical formulations.
• Nutritional Science: Studied as a metabolite in understanding the impact of dietary fats on phospholipid metabolism and related health outcomes.

Basic Information

Product Name	1-Linoleoyl-2-Hydroxy-Sn-Glycero-3-Phosphorylcholine
CAS No.	22252-07-9
Molecular Formula	C26H50NO7P
Molecular Weight	519.65 g/mol
Synonyms	LysoPC(18:2); 1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphocholine; Lysophosphatidylcholine (18:2); LPC(18:2); (2R)-2-Hydroxy-3-(phosphonooxy)propyl (9Z,12Z)-octadeca-9,12-dienoate; 2-Hydroxy-3-(trimethylammonio)propyl (9Z,12Z)-octadeca-9,12-dienoate phosphate; sn-Glycero-3-phosphocholine, 1-linoleoyl-2-hydroxy-; Linoleoyl lysophosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1-Linoleoyl-2-Hydroxy-Sn-Glycero-3-Phosphorylcholine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.