Description

Riboflavin 5'-(Dihydrogen Phosphate), Sodium Salt is the water-soluble, bioavailable phosphate ester derivative of vitamin B2 (riboflavin). This compound is a critical coenzyme precursor, essential for numerous metabolic redox reactions in living organisms. It is primarily utilized in the formulation of high-grade nutritional supplements, pharmaceutical preparations, and advanced cell culture media, serving the pharmaceutical, nutraceutical, and life science research industries.

Application

• Pharmaceutical Formulations: As an active pharmaceutical ingredient (API) or excipient in injectable solutions, tablets, and capsules to treat or prevent vitamin B2 deficiency.
• Nutraceuticals & Dietary Supplements: A key ingredient in high-potency vitamin B-complex supplements, energy drinks, and clinical nutrition products due to its superior bioavailability compared to riboflavin.
• Cell Culture & Microbiology: An essential growth factor in defined cell culture media, fermentation broths, and microbiological assays.
• Food & Beverage Fortification: Used for the nutritional fortification of infant formula, cereals, and health food products, often where a more soluble form is required.
• Biochemical Research: A vital reagent in enzymatic studies, particularly for flavoprotein enzymes like flavin mononucleotide (FMN)-dependent oxidoreductases.
• Cosmetic & Personal Care: Incorporated into skincare formulations for its antioxidant properties and role in cellular energy production.

Basic Information

Product Name	Riboflavin 5'-(Dihydrogen Phosphate), Sodium Salt
CAS No.	22251-85-0
Molecular Formula	C17H20N4NaO9P
Molecular Weight	478.33 g/mol
Synonyms	Flavin Mononucleotide Sodium Salt; FMN Sodium Salt; Riboflavin 5'-Monophosphate Sodium Salt; Riboflavin 5'-Phosphate Sodium Salt; Vitamin B2 Phosphate Sodium; Coenzyme R; Lactoflavin Phosphate Sodium; 10-(2',3',4',5'-Tetrahydroxypentyl)-7,8-dimethylisoalloxazine 5'-(Dihydrogen Phosphate) Sodium Salt
EINECS	244-871-1

Quality Control

Our Riboflavin 5'-(Dihydrogen Phosphate), Sodium Salt is manufactured under strict quality management systems. It is typically produced to meet exacting standards for pharmaceutical and food-grade applications, with specifications aligned to monographs such as USP/NF, Ph. Eur., and FCC. Each batch undergoes rigorous analytical testing including HPLC for purity, heavy metals screening, and microbiological examination. A comprehensive Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 8.0 %
pH (1% Solution)	5.0 - 7.0
Specific Rotation	-38.0° to -43.0° (c=1 in water)
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Microbiological Analysis	Meets standard for total aerobic count, yeasts & molds

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.