Description

(19R)-17,19-Epoxy-1-(Hydroxyacetyl)Curan-3-Ol CAS NO 22152-58-5 is a high-purity, semi-synthetic curane alkaloid derivative characterized by its specific stereochemistry and functional groups. This compound is a critical advanced intermediate in the synthesis of complex bioactive molecules, offering a versatile scaffold for pharmaceutical research and development. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and selectivity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the interaction of curane-derived compounds with biological receptors and enzymes.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for complex alkaloid-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(19R)-17,19-Epoxy-1-(Hydroxyacetyl)Curan-3-Ol
CAS No.	22152-58-5
Molecular Formula	C22H28N2O4
Molecular Weight	384.47 g/mol
Synonyms	1-(Hydroxyacetyl)-17,19-epoxycuran-3-ol (19R); 17,19-Epoxy-1-(hydroxyacetyl)curan-3-ol; Curan-3-ol, 17,19-epoxy-1-(hydroxyacetyl)-, (19R)-; (19R)-17,19-Epoxycuran-3-ol 1-(hydroxyacetate); 22152-58-5; A specific stereoisomer of a hydroxyacetyl curan epoxide.
EINECS	Contact for details

Quality Control

Our (19R)-17,19-Epoxy-1-(Hydroxyacetyl)Curan-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (IR, NMR, MS). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.