Description

Gentianaine CAS NO 22108-77-6 is a specialized alkaloid compound derived from the Gentiana species, known for its distinct chemical structure and biological activity. This high-purity intermediate is critical for research and development in advanced pharmaceutical synthesis, where precise molecular integrity is paramount. It serves as a key building block for medicinal chemists and manufacturers targeting neurological and metabolic pathways, ensuring reliable and consistent performance in complex formulations.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe compound in pharmacological and metabolic pathway studies.
• Natural Product Chemistry: Employed in the isolation, characterization, and derivatization of bioactive compounds from plant sources.
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories (HPLC, LC-MS).
• Preclinical Development: Utilized in the early-stage development of drug candidates targeting specific receptor sites.

Basic Information

Product Name	Gentianaine
CAS No.	22108-77-6
Molecular Formula	C₁₀H₉NO₄
Molecular Weight	207.18 g/mol
Synonyms	Gentianaine; 1H-Pyrido[3,4-b]indole-1-carboxylic acid, 3,4-dihydro-; 3,4-Dihydro-1H-pyrido[3,4-b]indole-1-carboxylic acid; (1S)-3,4-Dihydro-1H-pyrido[3,4-b]indole-1-carboxylic acid; Gentiaine; Gentianine (check isomer); Pyridindolizine derivative
EINECS	Contact for details

Quality Control

Our Gentianaine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP guidelines for pharmaceutical intermediates, and specifications can be aligned with client-specific pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.