Description

21α,22α-Epoxy-4-Hydroxy-19-Methyl-21,22-Dihydro-16,19-Secostrychnidine-10,16-Dione is a high-purity, structurally complex alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical advanced intermediate or reference standard for the development of novel bioactive molecules and analytical methods. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the exploration of nitrogen-containing heterocycles and their therapeutic potential.

Application

• Pharmaceutical Research & Development: As a key synthetic intermediate or building block for the creation of novel alkaloid-based drug candidates.
• Reference Standard Material: For use in analytical method development, validation, and quality control (QC) in laboratories studying related compounds.
• Medicinal Chemistry Studies: For structure-activity relationship (SAR) studies to understand the biological impact of specific functional groups on the secostrychnidine core.
• Academic & Institutional Research: In chemical biology and pharmacology projects investigating the properties and interactions of complex natural product derivatives.
• Fine Chemical Synthesis: As a specialized precursor for the custom synthesis of high-value, complex molecules for various industrial applications.

Basic Information

Product Name	21α,22α-Epoxy-4-Hydroxy-19-Methyl-21,22-Dihydro-16,19-Secostrychnidine-10,16-Dione
CAS No.	22029-94-3
Molecular Formula	C21H22N2O5
Molecular Weight	382.41 g/mol
Synonyms	21α,22α-Epoxy-4-hydroxy-19-methyl-21,22-dihydro-16,19-secostrychnidine-10,16-dione; 16,19-Secostrychnidine-10,16-dione, 21,22-epoxy-4-hydroxy-19-methyl-21,22-dihydro-, (21α,22α)-; Brucine N-oxide derivative; Strychnos alkaloid derivative; 10,16-Dioxo-21,22-epoxy-4-hydroxy-19-methyl-21,22-dihydro-16,19-secostrychnidine
EINECS	Contact for details

Quality Control

Our 21α,22α-Epoxy-4-Hydroxy-19-Methyl-21,22-Dihydro-16,19-Secostrychnidine-10,16-Dione is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound should be considered light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); handle and store under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.