Description

S-Butyrylthiocholine Chloride is a high-purity biochemical reagent, specifically a thiocholine ester derivative. This compound serves as a critical substrate for the determination of cholinesterase activity, particularly butyrylcholinesterase (BuChE), in diagnostic and research applications. It is essential for laboratories in the pharmaceutical, clinical diagnostics, and life science research sectors requiring precise enzyme kinetics and inhibitor studies.

Application

• Clinical Diagnostics: Primary substrate for the quantitative colorimetric or spectrophotometric assay of butyrylcholinesterase (pseudocholinesterase) activity in human serum or plasma.
• Pharmacological Research: Used in high-throughput screening (HTS) assays to evaluate the potency and mechanism of new cholinesterase inhibitors for conditions like Alzheimer's disease.
• Toxicology & Environmental Monitoring: Employed in standardized test kits to detect and quantify organophosphate and carbamate pesticide exposure by measuring cholinesterase inhibition.
• Biochemical Research: Essential reagent for kinetic studies, enzyme purification, and characterization of cholinesterase isoenzymes from various biological sources.
• In Vitro Diagnostic (IVD) Manufacturing: A key raw material in the formulation of ready-to-use diagnostic kits and reagents for automated clinical analyzers.
• Neuroscience Studies: Used in histochemical techniques for the localization of cholinesterase activity in tissue sections.

Basic Information

Product Name	S-Butyrylthiocholine Chloride
CAS No.	22026-63-7
Molecular Formula	C9H20ClNOS
Molecular Weight	225.78 g/mol
Synonyms	Butyrylthiocholine Chloride; BTC; S-BTC; S-BTCI; 2-Butanoylthioethyl(trimethyl)azanium Chloride; (2-Mercaptoethyl)trimethylammonium Chloride Butyrate Ester; Butyrylthiocholine Iodide (common related salt); Pseudocholinesterase Substrate
EINECS	244-741-4

Quality Control

Our S-Butyrylthiocholine Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for diagnostic and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Solubility	Clear, colorless solution in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.