Description

n-[4-[[1-(2-Amino-4-Hydroxy-6-Pteridinyl)Ethyl]Methylamino]Benzoyl]-L-Glutamic Acid is a high-purity folate derivative and a key intermediate in the synthesis of advanced pharmaceutical compounds. This compound is critical for research and development in targeted therapeutic areas, offering precise chemical functionality for molecular design. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on oncology, metabolic disorders, and nutritional science.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel folate-based drugs and targeted therapies.
• Biochemical Research: Used as a reference standard and reagent in studies involving folate metabolism, enzyme inhibition, and cellular pathways.
• Precision Medicine Development: Employed in the research and development of personalized medicine, particularly in oncology for drug targeting.
• Analytical Standard: Acts as a high-purity standard for quality control and method validation in HPLC, LC-MS, and other analytical techniques within pharmaceutical QC labs.
• Nutritional Science Research: Utilized in studies investigating advanced folate forms, bioavailability, and their role in human health.
• Fine Chemical Synthesis: A key starting material for the custom synthesis of complex, high-value molecules for clinical trial materials.

Basic Information

Product Name	n-[4-[[1-(2-Amino-4-Hydroxy-6-Pteridinyl)Ethyl]Methylamino]Benzoyl]-L-Glutamic Acid
CAS No.	22006-84-4
Molecular Formula	C₂₀H₂₅N₇O₆
Molecular Weight	459.46 g/mol
Synonyms	4-[[1-(2-Amino-4-hydroxy-6-pteridinyl)ethyl]methylamino]benzoyl-L-glutamic acid; L-Glutamic acid, N-[4-[[1-(2-amino-4-hydroxy-6-pteridinyl)ethyl]methylamino]benzoyl]-; Folate derivative intermediate; Pteroic acid glutamate derivative; 2-Amino-4-hydroxy-6-pteridinyl ethyl methylamino benzoyl glutamic acid; N-(4-(((1-(2-Amino-4-hydroxy-6-pteridinyl)ethyl)methylamino)benzoyl))-L-glutamic acid; (2S)-2-[[4-[[1-(2-Amino-4-oxo-1H-pteridin-6-yl)ethyl]methylamino]benzoyl]amino]pentanedioic acid
EINECS	Contact for details

Quality Control

Our n-[4-[[1-(2-Amino-4-Hydroxy-6-Pteridinyl)Ethyl]Methylamino]Benzoyl]-L-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.