Description

5'-Deoxy-5'-Thioinosine 5'-Monophosphate is a chemically modified nucleotide monophosphate derivative, serving as a critical building block and research tool in advanced biochemical synthesis. Its value lies in its role as a precursor for modified oligonucleotides and as a substrate for studying enzyme kinetics and nucleotide metabolism pathways. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic reagent production, where precise nucleotide analogs are required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Substrate for enzymatic studies, particularly for kinases and other nucleotide-processing enzymes.
• Oligonucleotide Synthesis: Building block for creating modified DNA/RNA sequences with altered backbone properties for therapeutic and diagnostic applications.
• Probe Development: Used in the development of labeled nucleotides for detection and diagnostic assays.
• Enzyme Inhibitor Studies: Serves as a tool compound to investigate the mechanism of action of nucleotide-mimicking drugs.
• Academic & Industrial R&D: Fundamental research material in medicinal chemistry and molecular biology laboratories.

Basic Information

Product Name	5'-Deoxy-5'-Thioinosine 5'-Monophosphate
CAS No.	21959-63-7
Molecular Formula	C10H13N4O6PS
Molecular Weight	348.27 g/mol
Synonyms	5'-Thioinosine monophosphate; 5'-Deoxy-5'-thio-IMP; 5'-S-Inosinic acid; 9-[(5-Thio-β-D-ribofuranosyl)purine-6-ol 5'-monophosphate]; 5'-Thio-IMP; dThio-IMP; 5'-Deoxy-5'-mercaptoinosine 5'-phosphate; Inosine 5'-(thiomonophosphate)
EINECS	Contact for details

Quality Control

Every batch of 5'-Deoxy-5'-Thioinosine 5'-Monophosphate is produced and tested under stringent quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific batch results for purity, impurities, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.