Description

Z-Ala-Gly-Gly-Oh is a protected tripeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of the alanyl-glycyl-glycine sequence. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), where it is used to introduce the Ala-Gly-Gly motif while protecting the N-terminus from unwanted side reactions. It is primarily utilized by pharmaceutical researchers, biotech companies, and fine chemical manufacturers engaged in the development and production of therapeutic peptides, biochemical probes, and advanced materials.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the controlled elongation of peptide chains in both research and GMP-scale production.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs, hormones, and enzyme inhibitors.
• Biochemical Tool Development: Serves as a precursor for fluorescent tags, affinity labels, or substrates for protease activity studies.
• Academic Research: Employed in university and institutional labs for studying peptide structure, function, and folding mechanisms.
• Custom Peptide Service Providers: A standard reagent for companies offering bespoke peptide synthesis services to the life science community.
• Material Science: Potential use as a monomer or cross-linker in the creation of bio-inspired polymers and hydrogels.

Basic Information

Product Name	Z-Ala-Gly-Gly-Oh
CAS No.	21929-69-1
Molecular Formula	C15H19N3O6
Molecular Weight	337.33 g/mol
Synonyms	N-Cbz-Ala-Gly-Gly-OH; N-Carbobenzoxy-L-alanylglycylglycine; Z-L-Ala-Gly-Gly-OH; Benzyloxycarbonyl-L-alanylglycylglycine; Cbz-Ala-Gly-Gly; Nα-Cbz-L-alanylglycylglycine; (Benzyloxycarbonyl)-L-alanyl-glycyl-glycine; Z-A-G-G-OH
EINECS	Contact for details

Quality Control

Our Z-Ala-Gly-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistency and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container should be kept sealed in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.