Description

Mono-p-Toluenesulfonate Urea is a specialized organic salt derived from urea and p-toluenesulfonic acid, serving as a versatile intermediate and reagent in fine chemical synthesis. Its value lies in its role as a controlled-release source of the tosyl group, a crucial protecting and activating agent in multi-step organic transformations. This compound is essential for research laboratories and industrial manufacturers engaged in producing pharmaceuticals, agrochemicals, and advanced materials where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfonamide or tosylate functionalities.
• Peptide Synthesis: Used as a coupling agent or protecting group reagent in solid-phase and solution-phase peptide chemistry.
• Agrochemical Production: Intermediate in the manufacture of herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Organic Synthesis Reagent: Employed in various reactions, including esterifications, etherifications, and nucleophilic substitutions as a tosylating agent.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of sulfonated dyes and colorants.

Basic Information

Product Name	Mono-p-Toluenesulfonate Urea
CAS No.	21835-55-2
Molecular Formula	C8H12N2O4S
Molecular Weight	232.26 g/mol
Synonyms	Urea p-Toluenesulfonate; Urea Tosylate; p-Toluenesulfonic Acid Urea Salt; 4-Methylbenzenesulfonic Acid - Urea (1:1); TS-Urea; UTS; Mono-tosylurea; N-Tosylurea
EINECS	Contact for details

Quality Control

Our Mono-p-Toluenesulfonate Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing all specification parameters, and our quality systems support compliance with cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in DMF, DMSO; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.