Description

(+)-Macronecine CAS NO 21824-61-3 is a high-purity pyrrolizidine alkaloid derivative, a key chiral building block and reference standard in advanced organic synthesis. This compound matters for its role in the research and development of complex natural products and pharmaceuticals, offering a defined stereochemical center for precise molecular construction. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex bioactive molecules and potential drug candidates.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related alkaloid compounds.
• Natural Product Research: Serves as a building block for the total synthesis or semi-synthesis of pyrrolizidine alkaloids and their analogs.
• Biochemical Research: Employed in studies investigating the biosynthesis, metabolism, or biological activity of pyrrolizidine-related compounds.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of specialty chemicals.

Basic Information

Product Name	(+)-Macronecine
CAS No.	21824-61-3
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(+)-Macronecine; Macronecine; (1R,7aR)-1-Hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl methanol; 1-Hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-ylmethanol; (7R,7aR)-7-(Hydroxymethyl)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-ol; L-Macronecine
EINECS	Contact for details

Quality Control

Our (+)-Macronecine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.