Description

(2ξ,17S,19E)-19,20-Didehydro-1-Demethyl-17-Hydroxyajmalan-16-Carboxylic Acid Methyl Ester is a high-purity, complex indole alkaloid derivative, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its specific stereochemistry and functional groups, which make it an essential building block for the research and development of novel therapeutic agents. This compound is primarily needed by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies focused on developing new alkaloid-based drugs and reference standards.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex indole alkaloids and potential active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and compound identification.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new derivatives with potential biological activity.
• Biochemical Research: Utilized as a tool compound in pharmacological studies to investigate interactions with biological targets.
• Fine Chemical Synthesis: Serves as a specialized starting material for the custom synthesis of other complex natural product analogs.

Basic Information

Product Name	(2ξ,17S,19E)-19,20-Didehydro-1-Demethyl-17-Hydroxyajmalan-16-Carboxylic Acid Methyl Ester
CAS No.	21641-60-1
Molecular Formula	C21H24N2O3
Molecular Weight	352.43 g/mol
Synonyms	19,20-Didehydro-1-demethyl-17-hydroxyajmalan-16-carboxylic acid methyl ester; Methyl (2ξ,17S,19E)-19,20-didehydro-1-demethyl-17-hydroxyajmalan-16-carboxylate; Ajmalan-16-carboxylic acid, 19,20-didehydro-1-demethyl-17-hydroxy-, methyl ester, (2ξ,17S,19E)-; 1-Demethyl-17-hydroxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester; 19,20-Didehydro-1-demethyl-17-hydroxyajmalan-16-methyl carboxylate; Ajmaline derivative intermediate; 21641-60-1
EINECS	Contact for details

Quality Control

Our (2ξ,17S,19E)-19,20-Didehydro-1-Demethyl-17-Hydroxyajmalan-16-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.