Description

3-(2-Aminoethyl)Indol-5-Ol Hydrochloride is a high-purity organic salt derivative of 5-hydroxytryptamine (serotonin), serving as a critical synthetic intermediate and reference standard. Its value lies in providing a stable, crystalline form of a key biochemical precursor, essential for precise research and manufacturing processes. This compound is primarily needed by pharmaceutical R&D teams, fine chemical manufacturers, and analytical laboratories engaged in neurochemical synthesis, drug discovery, and the development of diagnostic reagents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of serotonin receptor agonists, antagonists, and related central nervous system (CNS) active compounds.
• Biochemical Research: Used as a stable precursor or standard in studies of serotonin pathways, neurotransmission, and metabolic processes.
• Reference Standard: Serves as a high-purity calibrant for analytical methods such as HPLC, LC-MS, and NMR in quality control and forensic analysis.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex indole-based molecules, dyes, and specialized organic materials.
• Diagnostic Reagent Development: Utilized in the formulation of assays and kits for detecting and quantifying serotonin-related biomarkers.

Basic Information

Product Name	3-(2-Aminoethyl)Indol-5-Ol Hydrochloride
CAS No.	21591-86-6
Molecular Formula	C10H13ClN2O
Molecular Weight	212.67 g/mol
Synonyms	5-Hydroxytryptamine Hydrochloride; Serotonin Hydrochloride; 3-(2-Aminoethyl)-5-hydroxyindole Hydrochloride; 5-HT Hydrochloride; 5-Hydroxy-3-(2-aminoethyl)indole Hydrochloride; Enteramine Hydrochloride; Thrombocytin Hydrochloride
EINECS	244-456-1

Quality Control

Our 3-(2-Aminoethyl)Indol-5-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.