Description

2-Methylharmine is a specialized alkaloid derivative of the harmala family, known for its distinct chemical structure and potential as a key intermediate in advanced research. This compound matters for its role in the development of novel pharmacological agents and as a reference standard in analytical chemistry. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on neuroscience, medicinal chemistry, and phytochemical analysis.

Application

• Pharmaceutical Research & Development: Serves as a crucial intermediate or reference standard in the synthesis and study of novel bioactive compounds targeting neurological pathways.
• Medicinal Chemistry: Used as a building block or a lead compound for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Analytical Reference Standard: Employed in high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR) for method development, calibration, and quality control of related substances.
• Neuroscience Research: Investigated for its potential interactions with various receptor systems in preclinical studies.
• Fine Chemical Synthesis: Acts as a specialized precursor for the synthesis of more complex alkaloid derivatives and analogs.
• Academic & Institutional Research: Utilized in universities and research institutes for chemical, biological, and pharmacological studies.

Basic Information

Product Name	2-Methylharmine
CAS No.	21236-68-0
Molecular Formula	C₁₄H₁₄N₂O
Molecular Weight	226.28 g/mol
Synonyms	2-Methylharmine; 2-Methyl-7-methoxy-1-methyl-9H-pyrido[3,4-b]indole; 2-Methylharman; 2-Methyl-9H-pyrido[3,4-b]indole, 7-methoxy-1-methyl-; 7-Methoxy-1,2-dimethyl-9H-pyrido[3,4-b]indole; 2-Methyl-7-methoxy-β-carboline; 2-Methylharmane; 2-Methylharmaline (common misnomer, verify structure).
EINECS	Contact for details

Quality Control

Our 2-Methylharmine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.