Description

(1R)-2-Ethyl-1,2,3,4,6,11-Hexahydro-2α,5,7,12-Tetrahydroxy-6,11-Dioxo-1β-Naphthacenecarboxylic Acid Methyl Ester is a complex, highly functionalized naphthacene derivative, a key structural motif in several bioactive compounds. Its precise stereochemistry and array of functional groups make it a critical intermediate for advanced pharmaceutical synthesis and specialized chemical research. This compound is essential for R&D chemists and production units in the pharmaceutical and fine chemical industries focused on developing novel therapeutics and high-value specialty molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for antibiotics and antitumor agents.
• Chemical Research & Development: Used as a precursor or model compound in organic synthesis for studying novel reactions and constructing polycyclic frameworks.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related pharmaceutical compounds.
• Specialty Fine Chemical Production: Acts as an intermediate in the manufacture of high-value dyes, pigments, or functional materials requiring specific naphthacene-based structures.

Basic Information

Product Name	(1R)-2-Ethyl-1,2,3,4,6,11-Hexahydro-2α,5,7,12-Tetrahydroxy-6,11-Dioxo-1β-Naphthacenecarboxylic Acid Methyl Ester
CAS No.	21179-17-9
Molecular Formula	C24H24O8
Molecular Weight	440.44 g/mol
Synonyms	Methyl (1R)-2-ethyl-1,2,3,4,6,11-hexahydro-2α,5,7,12-tetrahydroxy-6,11-dioxo-1β-naphthacenecarboxylate; (1R,2S,4S)-4-Ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-1-naphthacenecarboxylic Acid Methyl Ester; 2-Ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-1-naphthacenecarboxylic Acid Methyl Ester (stereoisomer); 1β-Naphthacenecarboxylic acid derivative; Tetracycline-related intermediate
EINECS	Contact for details

Quality Control

Our (1R)-2-Ethyl-1,2,3,4,6,11-Hexahydro-2α,5,7,12-Tetrahydroxy-6,11-Dioxo-1β-Naphthacenecarboxylic Acid Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting R&D and cGMP-grade specifications where applicable. A detailed Certificate of Analysis (COA) confirming identity, purity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept tightly sealed in a dry environment and protected from prolonged exposure to light to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.