Description

3-Aminopyridine Adenine Dinucleotide is a chemically modified coenzyme analog of NAD+ (Nicotinamide Adenine Dinucleotide). This compound is a critical biochemical reagent used in enzymatic research and diagnostic applications where standard NAD+ is unsuitable. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic kit manufacturers for studying dehydrogenase enzymes and developing sensitive assay systems. Its modified structure offers unique reactivity profiles for specialized research protocols.

Application

• Enzymology Research: As a substrate or cofactor analog for studying the mechanism and kinetics of NAD+-dependent dehydrogenases.
• Diagnostic Assay Development: Used in the formulation of clinical chemistry reagents for measuring specific metabolites (e.g., ethanol, glucose, lactate) in automated analyzers.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) assays to identify potential inhibitors or activators of target enzymes for drug discovery.
• Biocatalysis: Serves as a cofactor in engineered enzymatic systems for the synthesis of chiral intermediates and fine chemicals.
• Metabolic Pathway Analysis: A tool for probing redox states and metabolic fluxes within cellular systems in biochemical research.

Basic Information

Product Name	3-Aminopyridine Adenine Dinucleotide
CAS No.	21106-96-7
Molecular Formula	C21H27N7O14P2
Molecular Weight	663.43 g/mol
Synonyms	3-Aminopyridine NAD+; 3-APAD; 3-Aminopyridine Adenine Dinucleotide Phosphate (oxidized form); AAD; 3-Aminopyridine NAD; 3-Pyridinamine Adenine Dinucleotide; NAD+ analog (3-amino); Coenzyme analog
EINECS	Contact for details

Quality Control

Our 3-Aminopyridine Adenine Dinucleotide is produced and tested under strict quality management systems. Each batch is characterized to ensure identity, purity, and functional performance suitable for research and in-vitro diagnostic use. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (HPLC), absorbance ratios, and moisture content. We adhere to cGMP guidelines for the manufacture of critical raw materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For extended storage under inert atmosphere, contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Absorbance Ratio (A260/A280)	2.10 - 2.20
Water (Karl Fischer)	≤ 5.0%
Solubility	Soluble in water, clear solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.