Description

Rel-1,2,3,4-Tetrahydronaphthalene-1α*,2α*-Diol is a chiral diol derivative of tetralin, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its rigid, fused-ring structure and stereochemistry make it a critical building block for creating complex molecules with specific three-dimensional orientations. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), chiral ligands, and other specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalysis: Used in the development of chiral ligands and organocatalysts for enantioselective synthesis.
• Fine Chemical Synthesis: Serves as a precursor for fragrances, agrochemicals, and other high-value specialty chemicals requiring a tetralin-based scaffold.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological development in organic synthesis and medicinal chemistry.
• Material Science: Potential monomer or building block for designing polymers and advanced materials with specific optical or structural properties.

Basic Information

Product Name	Rel-1,2,3,4-Tetrahydronaphthalene-1α*,2α*-Diol
CAS No.	21016-53-5
Molecular Formula	C₁₀H₁₂O₂
Molecular Weight	164.20 g/mol
Synonyms	(1R,2R)-1,2,3,4-Tetrahydronaphthalene-1,2-diol; (1R,2R)-1,2-Dihydroxy-1,2,3,4-tetrahydronaphthalene; rel-(1R,2R)-1,2,3,4-Tetrahydro-1,2-naphthalenediol; Tetralin-1,2-diol (rel-(1R,2R)-); (R,R)-Tetralin-1,2-diol (relative configuration); 1,2-Dihydroxytetralin; 1,2,3,4-Tetrahydro-1,2-naphthalenediol
EINECS	Contact for details

Quality Control

Our Rel-1,2,3,4-Tetrahydronaphthalene-1α*,2α*-Diol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, and NMR to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.