Description

2α-Methyl-5α-Cholestan-3α-Yl Thiocyanate is a high-purity steroidal thiocyanate derivative, a key synthetic intermediate in advanced organic and medicinal chemistry. Its value lies in providing a versatile chemical handle for the introduction of sulfur-containing functional groups into complex molecular scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life sciences sectors, particularly for developing novel bioactive molecules and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of novel steroidal drugs and bioactive compounds targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a building block in SAR studies and lead optimization for drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation plant growth regulators or pesticides with steroidal backbones.
• Biochemical Probe Synthesis: Utilized to create labeled or modified sterols for studying biological pathways and enzyme mechanisms.
• Organic Synthesis: Acts as a versatile reagent for introducing the thiocyanate moiety in complex multi-step synthetic routes.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	2α-Methyl-5α-Cholestan-3α-Yl Thiocyanate
CAS No.	20997-51-7
Molecular Formula	C₂₉H₄₉NS
Molecular Weight	443.77 g/mol
Synonyms	3α-Thiocyanato-2α-methyl-5α-cholestane; 2α-Methyl-5α-cholestan-3α-yl thiocyanate; (3α,5α)-2-Methylcholestan-3-yl thiocyanate; 5α-Cholestane-3α-thiocyanate, 2α-methyl-; 2α-Methylcholestan-3α-yl thiocyanate; NSC 163045; Thiocyanic acid, (2α-methyl-5α-cholestan-3α-yl) ester
EINECS	Contact for details

Quality Control

Every batch of 2α-Methyl-5α-Cholestan-3α-Yl Thiocyanate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are designed to meet the exacting requirements of research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.