Description

2-Naphthyl-β-D-Glucuronic Acid, Sodium Salt is a high-purity biochemical reagent widely used as a chromogenic substrate for enzymatic assays. Its core value lies in providing a sensitive and specific means to detect and quantify the activity of β-glucuronidase enzymes. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic industries, where precise enzyme measurement is critical for drug metabolism studies, microbial detection, and diagnostic test development.

Application

• Enzyme Substrate for β-Glucuronidase: Primary chromogenic substrate used in biochemical and microbiological assays to detect enzyme activity.
• Pharmaceutical Research: Utilized in drug metabolism and pharmacokinetic (DMPK) studies to investigate glucuronidation pathways.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for clinical and veterinary testing.
• Microbiological Identification: Employed in selective media and tests (e.g., for E. coli) to identify bacteria based on β-glucuronidase production.
• Biotechnology & Cell Biology: Used as a reporter substrate in molecular biology and genetic engineering applications.
• Food Safety & Environmental Testing: Applied in methods for the detection of fecal contamination in water and food samples.

Basic Information

Product Name	2-Naphthyl-β-D-Glucuronic Acid, Sodium Salt
CAS No.	20838-64-6
Molecular Formula	C₁₆H₁₅NaO₈
Molecular Weight	358.27 g/mol
Synonyms	2-Naphthyl β-D-Glucopyranosiduronic Acid Sodium Salt; 2-Naphthyl-β-D-glucuronide Sodium Salt; β-Glucuronidase Substrate (2-Naphthyl); 6-(2-Naphthyl)-β-D-glucopyranuronic Acid Sodium Salt; Sodium 2-Naphthyl β-D-Glucuronate; PNPG Sodium Salt (common abbreviation); 2-Naphthol-β-D-glucuronide Sodium Salt
EINECS	Contact for details

Quality Control

Our 2-Naphthyl-β-D-Glucuronic Acid, Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.