Description

Morphine 3-Acetate 6-β-D-Glucuronide 2,3,4-Triacetate Methyl Ester is a key synthetic intermediate and reference standard in the research and development of opioid pharmaceuticals. This compound is critical for analytical and metabolic studies, providing a protected form of morphine-6-glucuronide, a major active metabolite of morphine. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions focused on neuropharmacology, pain management, and forensic toxicology.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of morphine and its metabolites in drug development and quality control.
• Metabolic Pathway Research: Serves as a crucial intermediate in studies investigating the glucuronidation pathways and pharmacokinetics of opioid analgesics.
• Analytical Method Development: Essential for calibrating equipment and validating methods in HPLC, LC-MS, and GC-MS for forensic and clinical toxicology.
• Synthetic Chemistry Intermediate: Acts as a protected precursor in the organic synthesis of novel opioid derivatives or labeled compounds for tracer studies.
• Biochemical Research: Employed in in-vitro assays to study the binding affinity and activity of morphine glucuronides at opioid receptors.

Basic Information

Product Name	Morphine 3-Acetate 6-β-D-Glucuronide 2,3,4-Triacetate Methyl Ester
CAS No.	20736-12-3
Molecular Formula	C34H39NO15
Molecular Weight	701.67 g/mol
Synonyms	Morphine-6-glucuronide triacetate methyl ester; 3-Acetylmorphine-6-β-D-glucopyranuronoside 2,3,4-triacetate methyl ester; Morphine 3-acetate 6-glucuronide 2,3,4-triacetate methyl ester; 6-Glucuronide triacetate methyl ester of morphine 3-acetate; M6G triacetate methyl ester; (5α,6α)-7,8-Didehydro-4,5-epoxy-3-(acetyloxy)-17-methylmorphinan-6-yl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronic acid methyl ester
EINECS	Contact for details

Quality Control

Our Morphine 3-Acetate 6-β-D-Glucuronide 2,3,4-Triacetate Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive (store away from light). For long-term storage, consider keeping the container under inert atmosphere in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.