Description

All-trans-Retinonitrile is a synthetic derivative of vitamin A, specifically a nitrile analog of retinoic acid. This compound is valued for its role as a key intermediate and precursor in the synthesis of various retinoids and other bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, cosmetic, and nutraceutical industries for developing novel therapeutic and dermatological agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel retinoid-based drugs targeting dermatological conditions and certain cancers.
• Cosmetic R&D: Used in research for developing next-generation anti-aging and skin-rejuvenating cosmetic actives.
• Biochemical Research: Serves as a reference standard and a tool compound in studies of retinoid metabolism and receptor signaling pathways.
• Nutraceutical Development: Investigated as a precursor for potential vitamin A analogs with modified bioavailability or activity profiles.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex molecules due to its conjugated polyene structure.

Basic Information

Product Name	All-trans-Retinonitrile
CAS No.	20638-88-4
Molecular Formula	C20H27N
Molecular Weight	281.44 g/mol
Synonyms	Retinonitrile; all-trans-Retinyl nitrile; Vitamin A nitrile; Retinoic acid nitrile; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenenitrile; Axerophthen nitrile
EINECS	243-931-9

Quality Control

Our All-trans-Retinonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isomer profile confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Isomer Profile (HPLC)	All-trans isomer ≥ 95.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.