Description

Nitritocobalamin is a cobalt-containing coordination compound and a derivative of vitamin B12. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a precursor or intermediate in the synthesis of various cobalamin analogs. It serves as a critical material for researchers and manufacturers in the pharmaceutical, nutraceutical, and fine chemical synthesis sectors, particularly for those developing or producing specialized B12 formulations and investigating cobalt-based biochemistry.

Application

• Pharmaceutical Intermediate: Key starting material or precursor in the synthesis of active pharmaceutical ingredients (APIs) based on cobalamin (Vitamin B12).
• Biochemical Research: Used as a standard or reagent in laboratory studies investigating cobalt metabolism, enzyme cofactors, and B12-dependent pathways.
• Nutraceutical Manufacturing: Employed in the development and production of advanced vitamin B12 supplements and fortified food products.
• Fine Chemical Synthesis: Serves as a building block for creating specialized organometallic compounds and labeled analogs for diagnostic purposes.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or other spectroscopic methods.

Basic Information

Product Name	Nitritocobalamin
CAS No.	20623-13-6
Molecular Formula	C62H86CoN13O14P
Molecular Weight	1288.3 g/mol
Synonyms	Cob(III)alamin nitrite; Vitamin B12 nitrite; Nitritocobalamin(III); Cobalamin nitrite; α-(5,6-Dimethylbenzimidazolyl)cobamide nitrite; Coα-[α-(5,6-Dimethylbenzimidazolyl)]-Coβ-nitritocobamide; Nitritocob(III)alamin
EINECS	243-933-0

Quality Control

Our Nitritocobalamin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Dark red crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.