Description

[(2R,3S)-3-(2-Amino-4-Oxo-7,8-Dihydro-1H-Pteridin-6-Yl)-2,3-Dihydroxypropyl] (Hydroxy-Phosphonooxyphosphoryl) Hydrogen Phosphate is a high-purity, complex nucleotide derivative and a key intermediate in the synthesis of biologically active compounds. This product is critical for research and development in advanced pharmaceutical chemistry, particularly in the creation of novel therapeutics and enzyme cofactors. It is primarily sought by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of nucleoside analogs and metabolic pathway modulators.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside-based drugs and prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases and transferases.
• Cofactor Synthesis: Serves as a precursor in the preparation of specialized coenzymes and metabolic cofactors.
• Antiviral/Anticancer Agent Development: Employed in the R&D of therapeutic agents targeting viral replication or cellular proliferation pathways.
• Diagnostic Reagent Manufacturing: A component in the production of high-sensitivity diagnostic kits and assay reagents.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	[(2R,3S)-3-(2-Amino-4-Oxo-7,8-Dihydro-1H-Pteridin-6-Yl)-2,3-Dihydroxypropyl] (Hydroxy-Phosphonooxyphosphoryl) Hydrogen Phosphate
CAS No.	20574-65-6
Molecular Formula	C10H17N5O13P3
Molecular Weight	508.18 g/mol
Synonyms	Dihydrofolate Diphosphate; 7,8-Dihydrofolate triphosphate; (2R,3S)-3-(2-Amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)-2,3-dihydroxypropyl trihydrogen triphosphate; 7,8-Dihydrofolic acid triphosphate; H2folate triphosphate; Dihydroperoyl triphosphate; NSC 113928; Dihydrofolate-PPP
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards required for pharmaceutical R&D and fine chemical synthesis. Our quality protocols are designed to support cGMP compliance where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.