Description

1-Tridecanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity lysophospholipid, specifically a lysophosphatidylcholine (LPC) with a defined C13:0 acyl chain. This compound is a critical biochemical tool and a key intermediate for the synthesis of more complex phospholipids and lipid-based drug delivery systems. It is essential for researchers and manufacturers in pharmaceutical development, lipidomics, and advanced material science who require structurally defined lipids for reproducible results. Its precise structure enables studies on membrane biophysics, lipid signaling, and the formulation of liposomes and lipid nanoparticles.

Application

• Lipidomics Research & Biomarker Discovery: Used as a standard or internal standard in mass spectrometry for the identification and quantification of lysophosphatidylcholines in biological samples.
• Pharmaceutical Excipient & Drug Delivery: Serves as a key component in the formulation of liposomes, solid lipid nanoparticles (SLNs), and other lipid-based carriers for enhancing drug solubility and targeted delivery.
• Biochemical Research: Employed as a substrate or modulator in enzymatic assays and studies of phospholipase A2 (PLA2) activity, lipid signaling pathways, and membrane protein interactions.
• Synthetic Lipid Chemistry: Acts as a crucial building block for the semi-synthesis of asymmetric or labeled phosphatidylcholines and other complex phospholipids.
• Cell Culture & Membrane Studies: Used to modify membrane fluidity and properties in model membrane systems (e.g., vesicles, supported lipid bilayers) for biophysical research.
• Cosmetic Formulations: Incorporated into high-end skincare products for its emulsifying properties and potential skin barrier repair functions.

Basic Information

Item	Detail
Product Name	1-Tridecanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine
CAS No.	20559-17-5
Molecular Formula	C21H44NO7P
Molecular Weight	453.55 g/mol
Synonyms	1-Myristoyl-2-hydroxy-sn-glycero-3-phosphocholine (common misnomer for C13:0); LysoPC(13:0/0:0); 1-Tridecanoyl-2-lyso-sn-glycero-3-phosphocholine; Lysophosphatidylcholine(13:0); LPC(13:0); 2-Hydroxy-1-tridecanoyl-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine, 1-tridecanoyl-2-hydroxy-; Tridecanoyl lysophosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1-Tridecanoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards required for research and cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere (argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (by Phosphorus)	≥ 98% (on anhydrous basis)
Water Content (KF)	≤ 2.0 %
Solvent Residue (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.