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1-Myristoyl-Sn-Glycero-3-Phosphocholine CAS NO 20559-16-4


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CAS No.:20559-16-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Myristoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid belonging to the lysophosphatidylcholine (LPC) class, specifically a 14-carbon saturated fatty acid chain (myristoyl) derivative. This compound is a critical building block and model membrane component in advanced life science research and pharmaceutical development. It is essential for researchers and formulators in liposome preparation, membrane biophysics studies, and drug delivery system development, where precise lipid composition dictates performance.

Application

  • Liposome & Lipid Nanoparticle (LNP) Formulation: A key component for creating model membranes and designing drug delivery vesicles for nucleic acids, vaccines, and small molecules.
  • Membrane Biophysics Research: Used as a standard or modifier in studies of membrane fluidity, phase behavior, and protein-lipid interactions.
  • Cell Biology & Signaling Studies: Investigated for its role as a bioactive lysophospholipid mediator in cellular processes.
  • Pharmaceutical Excipient: Potential use as a solubilizing agent or permeation enhancer in advanced parenteral and topical formulations.
  • Biochemical Reagent: Serves as a substrate or intermediate in enzymatic assays for phospholipase activity.
  • Analytical Standard: Employed as a reference standard in HPLC, LC-MS, and other analytical methods for lipidomics and quality control.

Basic Information

Item Details
Product Name 1-Myristoyl-Sn-Glycero-3-Phosphocholine
CAS No. 20559-16-4
Molecular Formula C22H46NO7P
Molecular Weight 467.57 g/mol
Synonyms Lyso-myristoyl Phosphatidylcholine; LPC(14:0); 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphocholine; 1-Tetradecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; Myristoyl Lysophosphatidylcholine; 14:0 LPC; Lysophosphatidylcholine (14:0/0:0); sn-Glycero-3-phosphocholine, 1-myristoyl derivative
EINECS Contact for details

Quality Control

Our 1-Myristoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95%
Loss on Drying ≤ 2.0 %
Solubility Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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