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Cytidine 2',3'-Phosphoric Acid Potassium Salt CAS NO 20486-23-1


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CAS No.:20486-23-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Cytidine 2',3'-Phosphoric Acid Potassium Salt is a high-purity nucleotide derivative, a key intermediate in biochemical research and pharmaceutical synthesis. Its primary value lies in its role as a protected cytidine phosphate, essential for the controlled synthesis of oligonucleotides and nucleotide analogs. This compound is critically needed by research institutions and pharmaceutical developers focused on nucleic acid chemistry, antiviral drug development, and molecular biology applications.

Application

  • Oligonucleotide Synthesis: Serves as a crucial phosphoramidite precursor or protected monomer for solid-phase synthesis of DNA and RNA sequences.
  • Pharmaceutical Intermediate: Used in the research and development of nucleoside-based antiviral and anticancer therapeutics.
  • Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies involving kinases, polymerases, and other nucleic acid-metabolizing enzymes.
  • Pro-drug Development: Utilized to create masked or more bioavailable forms of cytidine-based active pharmaceutical ingredients (APIs).
  • Diagnostic Reagent Manufacturing: A component in the production of labeled nucleotides for diagnostic assays and sequencing.
  • Reference Standard: Employed as a high-purity analytical standard for quality control in nucleotide production.

Basic Information

Product Name Cytidine 2',3'-Phosphoric Acid Potassium Salt
CAS No. 20486-23-1
Molecular Formula C9H13KN3O8P
Molecular Weight 361.29 g/mol
Synonyms Cytidine 2',3'-Cyclic Monophosphate Potassium Salt; 2',3'-cCMP Potassium Salt; Cytidine 2',3'-Cyclic Phosphate Potassium Salt; 2',3'-Cyclic Cytidylic Acid Potassium Salt; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3,4-dihydro-2H-furan-2-yl]-4-amino-2-oxo-1,2-dihydropyrimidin-1-ium 2,3-Cyclic Phosphate Potassium Salt; Cytidine 2',3'-Cyclic Monophosphoric Acid Potassium Salt; 2',3'-Cyclic Cytidine Monophosphate K+ Salt
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Quality Control

Our Cytidine 2',3'-Phosphoric Acid Potassium Salt is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and stringent tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Heavy Metals ≤ 10 ppm
Residual Solvents (GC) Meets ICH guidelines
pH (1% Solution) 6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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