Description

Deprodone Propionate is a synthetic corticosteroid ester with potent anti-inflammatory and antipruritic properties. This compound is valued for its targeted therapeutic action and is a critical active pharmaceutical ingredient (API) in advanced topical formulations. It is primarily required by pharmaceutical manufacturers and research institutions developing treatments for dermatological conditions such as eczema, psoriasis, and allergic contact dermatitis.

Application

• Topical Corticosteroid Formulations: As the key API in creams, ointments, and lotions for treating inflammatory skin disorders.
• Veterinary Dermatology: Used in medicated sprays and topical preparations for managing skin inflammation and allergies in animals.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of more complex steroid-based pharmaceuticals.
• Clinical Research: Employed in preclinical and clinical studies to investigate mechanisms of steroid action and develop new anti-inflammatory therapies.
• Compounding Pharmacy: Utilized by specialized pharmacies to prepare customized topical medications for specific patient needs.

Basic Information

Product Name	Deprodone Propionate
CAS No.	20424-00-4
Molecular Formula	C24H32O5
Molecular Weight	400.51 g/mol
Synonyms	Desoximetasone Propionate; 9α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-propionate; 11β,21-Dihydroxy-9α-fluoro-16α-methylpregna-1,4-diene-3,20-dione 21-propionate; Desoxymethasone Propionate; Deprodone; Topicon (trade name component); Desoximetasone 21-propionate
EINECS	243-818-7

Quality Control

Our Deprodone Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with every shipment to guarantee supply reliability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment away from direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.