Description

(13β,14β)-7,8-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylhasubanan-6α,9α-Diol CAS NO 20377-55-3 is a complex, semi-synthetic alkaloid derivative belonging to the hasubanan class, a group of compounds known for their intricate polycyclic structures. This compound matters as a high-value chemical intermediate and a key reference standard for research into novel pharmaceutical agents, particularly those targeting neurological pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers engaged in the synthesis of advanced bioactive molecules.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel opioid receptor modulators and other central nervous system (CNS) active compounds.
• Reference Standard for Analytical Chemistry: Used as a high-purity standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related substances.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to explore the pharmacological profile of hasubanan alkaloid derivatives.
• Process Chemistry & Scale-Up: Acts as a building block for the pilot-scale and commercial-scale production of specialized active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Utilized in universities and research institutes for studying alkaloid biosynthesis, chemical synthesis pathways, and novel organic reactions.
• Biochemical Assay Development: Applied in the development of in vitro screening assays for receptor binding studies and enzymatic activity tests.

Basic Information

Product Name	(13β,14β)-7,8-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylhasubanan-6α,9α-Diol
CAS No.	20377-55-3
Molecular Formula	C20H25NO4
Molecular Weight	343.42 g/mol
Synonyms	17-Methylhasubanan-6α,9α-diol, 7,8-didehydro-4,5α-epoxy-3-methoxy-, (13β,14β)-; 7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylhasubanan-6α,9α-diol; Hasubanan derivative; 20377-55-3; (13beta,14beta)-7,8-Didehydro-4,5alpha-epoxy-3-methoxy-17-methylhasubanan-6alpha,9alpha-diol
EINECS	Contact for details

Quality Control

Our (13β,14β)-7,8-Didehydro-4,5α-Epoxy-3-Methoxy-17-Methylhasubanan-6α,9α-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. For research and pharmaceutical development purposes, we can supply material that meets in-house reference standard specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, storage at 2-8°C is recommended. The container should be kept in a well-ventilated area and handled in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.