Description

(1α,8β,12ξ,13ξ,15E)-1,2-Dihydro-12-Hydroxysenecionan-11,16-Dione is a complex pyrrolizidine alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a key intermediate or reference standard for developing novel bioactive molecules, particularly in the study of natural product chemistry and medicinal chemistry. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on high-value specialty chemicals and active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex alkaloid-based drug candidates.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical and phytochemical laboratories.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies targeting specific biological pathways.
• Natural Product Synthesis: Employed in the total or semi-synthesis of complex natural products for biological evaluation.
• Biochemical Research: Used as a tool compound to investigate enzyme interactions and metabolic processes related to pyrrolizidine alkaloids.
• Fine Chemical Production: Acts as a specialty intermediate for the manufacture of high-value, low-volume chemicals for niche markets.

Basic Information

Item	Details
Product Name	(1α,8β,12ξ,13ξ,15E)-1,2-Dihydro-12-Hydroxysenecionan-11,16-Dione
CAS No.	20361-77-7
Molecular Formula	C18H25NO5
Molecular Weight	335.40 g/mol
Synonyms	12-Hydroxysenecionan-11,16-dione; Senecionine derivative; 1,2-Dihydro-12-hydroxysenecionan-11,16-dione; (1alpha,8beta,12xi,13xi,15E)-1,2-Dihydro-12-hydroxysenecionan-11,16-dione; Pyrrolizidine alkaloid intermediate; PA reference standard; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1α,8β,12ξ,13ξ,15E)-1,2-Dihydro-12-Hydroxysenecionan-11,16-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.