Description

Argyrophilic Acid CAS NO 20316-84-1 is a specialized organic compound primarily recognized for its role as a histochemical staining agent. This compound is valued for its selective interaction with silver ions, enabling the visualization of specific cellular and tissue components under a microscope. It is an essential reagent for researchers and laboratories in the fields of histology, pathology, and neuroscience, where precise cellular identification is critical.

Application

• Histological Staining: Key component in silver staining protocols for visualizing reticular fibers, nerve endings, and neurofibrillary tangles in tissue sections.
• Neuropathology Research: Used in specialized stains to study neurodegenerative diseases, such as Alzheimer's, by highlighting pathological protein aggregates.
• Diagnostic Pathology: Employed in laboratory settings to aid in the diagnosis of certain tumors and connective tissue disorders through enhanced tissue contrast.
• Biomedical Research: Serves as a critical reagent in experimental studies investigating cellular structure and the extracellular matrix.
• Microscopy & Imaging: Facilitates high-contrast imaging for photographic documentation and analysis in life science research.

Basic Information

Product Name	Argyrophilic Acid
CAS No.	20316-84-1
Molecular Formula	C14H12N2O4
Molecular Weight	272.26 g/mol
Synonyms	3-Hydroxy-4-[(2-hydroxy-1-naphthyl)azo]naphthalene-1-sulfonic acid; 1-Naphthalenesulfonic acid, 3-hydroxy-4-[(2-hydroxy-1-naphthyl)azo]-; Argyrophil; Argyrophile; Silver stain reagent; Bielschowsky stain component; Reticulin stain reagent; Neurofibrillary tangle stain
EINECS	Contact for details

Quality Control

Our Argyrophilic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and performance in sensitive staining applications. Each lot is tested for critical parameters including identity, purity, and staining performance. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	Dark brown to black powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Staining Performance	Meets reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.