Description

Chelidonine Monohydrate is a naturally occurring benzylisoquinoline alkaloid derivative, isolated from plants of the *Chelidonium majus* species. This compound serves as a critical reference standard and key intermediate in pharmaceutical research and development, particularly for its bioactive properties. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in alkaloid chemistry, pharmacology studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for qualitative and quantitative analysis in method development and quality control of herbal extracts and pharmaceutical formulations.
• Biochemical Research: Serves as a key reagent in pharmacological studies investigating its effects on cellular processes and enzyme interactions.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a building block in the synthetic pathways for more complex pharmaceutical compounds.
• Natural Product Isolation & Purification: Employed as a benchmark in the extraction, isolation, and purification processes of related plant alkaloids.
• Academic & Industrial R&D: Fundamental for exploratory research in medicinal chemistry and the development of new drug candidates.

Basic Information

Product Name	Chelidonine Monohydrate
CAS No.	20267-87-2
Molecular Formula	C₂₀H₁₉NO₅·H₂O
Molecular Weight	353.37 g/mol (monohydrate)
Synonyms	Chelidonine hydrate; (-)-Chelidonine monohydrate; Stylophorin hydrate; 13-Methylchelidonine monohydrate; (13S)-13-Methyl-5,6,13,13a-tetrahydro-9,10-dimethoxy-6-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-8-ol monohydrate; α-Homochelidonine monohydrate; NSC 172112 monohydrate
EINECS	Contact for details

Quality Control

Our Chelidonine Monohydrate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by spectroscopic methods, and control of residual solvents and moisture. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	4.5% - 6.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.