Description

Piperlongumine is a potent, naturally occurring alkaloid and bioactive compound derived from the long pepper plant (*Piper longum*). This molecule is of significant commercial and research interest due to its selective cytotoxicity against cancer cells while sparing normal cells, making it a valuable lead compound in pharmaceutical development. It is primarily sought after by research institutions, pharmaceutical R&D departments, and manufacturers of high-purity fine chemicals for applications in oncology research, nutraceuticals, and as a biochemical tool.

Application

• Pharmaceutical Research & Development: As a key investigational compound in preclinical studies for its anti-cancer, anti-inflammatory, and anti-platelet aggregation properties.
• Oncology Research Reagents: Used in cell culture and animal studies to investigate mechanisms of selective cancer cell death and potential chemotherapeutic applications.
• Nutraceutical and Dietary Supplement Formulation: Incorporated into advanced supplements targeting cellular health and inflammation modulation, given its natural origin.
• Biochemical Tool Compound: Employed in laboratory settings to study reactive oxygen species (ROS)-mediated pathways and stress response signaling in various disease models.
• Fine Chemical Synthesis: Serves as a sophisticated intermediate or reference standard for the synthesis of novel derivatives with enhanced bioactivity.
• Academic Research: Utilized in universities and research institutes for pharmacological and phytochemical studies.

Basic Information

Product Name	Piperlongumine
CAS No.	20069-09-4
Molecular Formula	C17H19NO5
Molecular Weight	317.34 g/mol
Synonyms	Piplartine; (2E,4E)-5-(5,6-Dihydro-1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one; 5,6-Dihydro-1-[(2E,4E)-5-(5,6-dihydro-1,3-benzodioxol-5-yl)-2,4-pentadienoyl]-2(1H)-pyridinone; Piperlonguminine; Longumine
EINECS	Contact for details

Quality Control

Our Piperlongumine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods (IR, NMR). We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical research applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider sealing under an inert atmosphere such as nitrogen or argon to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.