Description

4-[(5S,7S,8S,10S,13R,17R)-3,7,12-Trihydroxy-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-17-Yl]Pentanoic Acid is a high-purity steroidal acid derivative of significant interest in advanced pharmaceutical research and synthesis. This compound serves as a critical chiral intermediate for the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease. It is essential for research institutions and pharmaceutical manufacturers engaged in the synthesis of complex steroid-based molecules, where precise stereochemistry and purity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and hormone receptor research.
• Process Development: Serves as a starting material or intermediate for scaling up the production of specialized steroidal compounds.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry projects and novel compound library generation.

Basic Information

Product Name	4-[(5S,7S,8S,10S,13R,17R)-3,7,12-Trihydroxy-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-17-Yl]Pentanoic Acid
CAS No.	2955-27-3
Molecular Formula	C24H40O5
Molecular Weight	408.58 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid; Cholic Acid (5β,3α,7α,12α-isomer); Cholanoic Acid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)-; (3α,5β,7α,12α)-3,7,12-Trihydroxycholan-24-oic Acid; 5β-Cholanic Acid-3α,7α,12α-triol; 3,7,12-Trihydroxy-5β-cholan-24-oic Acid; 5β-Cholan-24-oic Acid, 3α,7α,12α-trihydroxy-; Cholic Acid (specified stereoisomer)
EINECS	220-971-6

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, stereochemical purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.