Description

Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-Hydroxy-11,17-Dimethoxyyohimban-16-Carboxylate is a complex yohimbane alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate for the development of novel therapeutic agents targeting the central nervous and cardiovascular systems. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel alkaloid-based drug candidates for neurological and cardiovascular indications.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies investigating adrenergic and serotonergic receptor interactions.
• Organic Synthesis: Serves as a sophisticated chiral template for the total synthesis of complex natural products and for exploring new synthetic methodologies.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for the production of high-value active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of yohimbane alkaloids.

Basic Information

Product Name	Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-Hydroxy-11,17-Dimethoxyyohimban-16-Carboxylate
CAS No.	2901-66-8
Molecular Formula	C23H28N2O5
Molecular Weight	412.48 g/mol
Synonyms	Methyl 18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate; 16-Carbomethoxy-18-hydroxy-11,17-dimethoxyyohimban; Methyl (3β,16β,17α,18β,20α)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate; 11,17-Dimethoxy-18-hydroxyyohimban-16-carboxylic acid methyl ester; Yohimbane-16-carboxylic acid, 18-hydroxy-11,17-dimethoxy-, methyl ester, (3β,16β,17α,18β,20α)-; 2901-66-8; 18-Hydroxy-11,17-dimethoxyyohimban-16-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-Hydroxy-11,17-Dimethoxyyohimban-16-Carboxylate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and detailed Certificates of Analysis (COA) to support your research and development needs, ensuring reliable and consistent quality for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.