Description

Cholan-24-Oic Acid, 3,7-Dihydroxy-, Monosodium Salt, (3A,5B,7B)- is a high-purity, water-soluble bile acid derivative, also known as Sodium Glycochenodeoxycholate. This compound is a critical biochemical reagent and pharmaceutical intermediate valued for its role in facilitating the solubilization and absorption of lipids and fat-soluble vitamins. It is essential for research and manufacturing in the pharmaceutical, biotechnology, and diagnostic sectors, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediates: A key starting material or intermediate in the synthesis of therapeutic bile acids and related steroid-based pharmaceuticals.
• Biochemical Research: Used as a critical reagent in cell biology and biochemistry studies, particularly for membrane protein solubilization and lipid metabolism research.
• Diagnostic Reagents: Employed as a component in in-vitro diagnostic kits and assays for liver function and metabolic studies.
• Cell Culture & Media: Acts as a surfactant or solubilizing agent in specialized cell culture media formulations.
• Reference Standard: Serves as a certified reference material (CRM) or analytical standard for quality control in pharmaceutical and research laboratories.
• Lipid & Micelle Studies: Utilized in the preparation of micelles and mixed micelles for studying drug delivery systems and membrane dynamics.

Basic Information

Product Name	Cholan-24-Oic Acid, 3,7-Dihydroxy-, Monosodium Salt, (3A,5B,7B)-
CAS No.	2898-95-5
Molecular Formula	C26H43NaO5
Molecular Weight	458.61 g/mol
Synonyms	Sodium Glycochenodeoxycholate; Glycochenodeoxycholic Acid Sodium Salt; N-(3α,7α-Dihydroxy-5β-cholan-24-oyl)glycine Sodium Salt; Chenodeoxycholylglycine Sodium Salt; GCDC Sodium Salt; Sodium Chenodeoxycholylglycinate; NSC 113233
EINECS	220-787-8

Quality Control

Our Cholan-24-Oic Acid, 3,7-Dihydroxy-, Monosodium Salt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatograms and specifications are provided for every shipment, ensuring full traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details
Solubility	Soluble in water and alcohol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.