Description

Thymidine 3',5'-Diphosphate is a high-purity nucleotide derivative essential for biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool in the study of nucleic acid metabolism and enzyme mechanisms. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and diagnostic industries for applications ranging from enzymatic synthesis to molecular biology.

Application

• Biochemical Research: As a substrate or inhibitor in enzymatic studies, particularly for nucleotidyltransferases and kinases.
• Pharmaceutical Intermediates: Used in the synthesis of nucleotide-based prodrugs and antiviral agents.
• Molecular Biology: A key component in the study of DNA repair mechanisms and nucleic acid biochemistry.
• Diagnostic Reagent Manufacturing: Employed in the production of reagents for enzymatic assays and diagnostic kits.
• Enzyme Characterization: Essential for kinetic studies and determining the specificity of phosphodiesterases and related enzymes.
• Metabolic Pathway Analysis: A tool for investigating nucleotide salvage pathways and cellular metabolism.

Basic Information

Product Name	Thymidine 3',5'-Diphosphate
CAS No.	2863-04-9
Molecular Formula	C10H15N2O11P2
Molecular Weight	401.18 g/mol
Synonyms	Thymidine 3',5'-Diphosphate; Thymidine 3',5'-Bisphosphate; 3',5'-dTDP; TDP; Thymidine-3',5'-diphosphoric Acid; 5'-Thymidylic Acid, 3'-(Dihydrogen Phosphate); Thymidine 5'-(Trihydrogen Diphosphate) 3'-(Dihydrogen Phosphate); pdTp
EINECS	220-687-4

Quality Control

Our Thymidine 3',5'-Diphosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture to ensure it meets the stringent requirements of research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.