Description

(R)-1-(2-Piperidyl)Acetone is a high-value chiral intermediate characterized by its piperidine-based structure and ketone functionality. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, enabling the production of enantiomerically pure pharmaceuticals. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Used in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric excess.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in fine chemical manufacturing.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure pesticides and herbicides.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-1-(2-Piperidyl)Acetone
CAS No.	2858-66-4
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	(R)-1-(Piperidin-2-yl)propan-2-one; (R)-2-Acetonylpiperidine; (R)-1-(2-Piperidinyl)-2-propanone; (R)-2-(2-Oxopropyl)piperidine; (R)-1-Piperidin-2-ylacetone; (2R)-1-(Piperidin-2-yl)propan-2-one; (R)-(-)-1-(2-Piperidyl)acetone
EINECS	220-685-5

Quality Control

Our (R)-1-(2-Piperidyl)Acetone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a highly volatile compound, store in a cool, well-ventilated place. Recommended long-term storage temperature is 2-8°C. Keep away from strong bases and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.