Description

Ergostine CAS NO 2854-38-8 is a high-purity, specialized ergot alkaloid derivative of significant interest in advanced research and development. This compound serves as a critical intermediate and reference standard for the synthesis and study of complex bioactive molecules. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical sectors for applications in medicinal chemistry, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents and complex active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and precursor in studies investigating alkaloid biosynthesis, receptor interactions, and structure-activity relationships (SAR).
• Process Development: Employed in the optimization and scale-up of synthetic routes for ergot-derived compounds in fine chemical manufacturing.
• Analytical Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development using HPLC, LC-MS, and other techniques.
• Academic & Contract Research: Supports investigative work in university laboratories and contract research organizations (CROs) focused on natural product chemistry.

Basic Information

Product Name	Ergostine
CAS No.	2854-38-8
Molecular Formula	C32H41N5O5
Molecular Weight	575.70 g/mol
Synonyms	Ergostine; 12'-Hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione; (5'α)-12'-Hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione; Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)-, (5'α)-; Dihydroergocristine impurity; Dihydroergocristine related compound A
EINECS	220-672-5

Quality Control

Our Ergostine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of specific impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.