Description

Mesaconitine is a diterpenoid alkaloid, a key bioactive constituent found in plants of the *Aconitum* genus. This high-purity reference standard is critical for analytical research, quality control, and pharmacological studies due to its significant biological activity. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and analytical service providers working on natural product chemistry, toxicology, and drug discovery.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the identification and quantification of mesaconitine in herbal medicines, extracts, and finished products.
• Biochemical Research: Used in pharmacological studies to investigate its effects on ion channels, neurotoxicity, and potential analgesic or anti-inflammatory properties.
• Quality Control & Assurance: Essential for HPLC, LC-MS, and TLC methods development and validation in the quality control of *Aconitum*-based traditional medicines and supplements.
• Toxicological Studies: Employed as a standard in forensic and clinical toxicology to detect and measure aconitine alkaloid poisoning.
• Natural Product Isolation: Acts as a marker compound for the standardization and authentication of plant extracts in the nutraceutical industry.
• Academic Research: Used in universities and research institutes for studies in phytochemistry, biosynthesis, and structural-activity relationships (SAR) of diterpenoid alkaloids.

Basic Information

Product Name	Mesaconitine
CAS No.	2752-64-9
Molecular Formula	C33H45NO11
Molecular Weight	631.71 g/mol
Synonyms	Mesaconitine; 3-Deoxyaconitine; 8-Acetyl-14-benzoylmesaconine; (1α,3α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate
EINECS	220-406-5

Quality Control

Every batch of our Mesaconitine is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research and reference materials. A detailed Certificate of Analysis (COA) is supplied with each shipment, which includes results from HPLC, MS, and NMR analyses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.