Description

17-Oxoyohimban-16α-Carboxylic Acid Methyl Ester is a key synthetic intermediate in the production of complex indole alkaloids and pharmaceutical compounds. Its value lies in its role as a versatile building block for the synthesis of active pharmaceutical ingredients (APIs) and for advanced research in medicinal chemistry. This compound is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex indole alkaloid-based drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for the design, synthesis, and structure-activity relationship (SAR) studies of novel therapeutic compounds.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals and high-value organic compounds requiring the yohimbane or oxindole structural framework.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating alkaloid biosynthesis pathways and the biological activity of related natural products.

Basic Information

Product Name	17-Oxoyohimban-16α-Carboxylic Acid Methyl Ester
CAS No.	2671-57-0
Molecular Formula	C21H24N2O3
Molecular Weight	352.43 g/mol
Synonyms	Methyl 17-oxoyohimban-16α-carboxylate; 16α-Carbomethoxy-17-oxoyohimban; 16α-Methoxycarbonyl-17-oxoyohimban; Methyl (16α)-17-oxoyohimban-16-carboxylate; 17-Oxo-16α-carbomethoxyyohimban; Yohimban-16α-carboxylic acid, 17-oxo-, methyl ester; 17-Oxoyohimban-16-carboxylic acid methyl ester (16α)
EINECS	Contact for details

Quality Control

Our 17-Oxoyohimban-16α-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates and research chemicals. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.