Description

(16R)-17-(Acetoxy)-2α,5α-Epoxy-1,2-Dihydroakuammilan-16-Carboxylic Acid Methyl Ester is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex natural product analogs and potential therapeutic agents.
• Reference Standard: Used for qualitative and quantitative analysis in HPLC, LC-MS, and NMR to ensure product identity and purity in research and quality control laboratories.
• Medicinal Chemistry Research: A valuable substrate for structure-activity relationship (SAR) studies targeting neurological or other biological pathways.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of akuammilan-based compounds.
• Academic Research: Used in universities and institutes for studies in organic synthesis, alkaloid chemistry, and natural product isolation.

Basic Information

Product Name	(16R)-17-(Acetoxy)-2α,5α-Epoxy-1,2-Dihydroakuammilan-16-Carboxylic Acid Methyl Ester
CAS No.	2671-32-1
Molecular Formula	C23H28N2O6
Molecular Weight	428.48 g/mol
Synonyms	Methyl (16R)-17-acetoxy-2α,5α-epoxy-1,2-dihydroakuammilan-16-carboxylate; 2α,5α-Epoxy-1,2-dihydroakuammilan-16-carboxylic acid, 17-(acetyloxy)-, methyl ester, (16R)-; Akuammilan derivative; Indole alkaloid ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (16R)-17-(Acetoxy)-2α,5α-Epoxy-1,2-Dihydroakuammilan-16-Carboxylic Acid Methyl Ester is produced and analyzed under strict quality management protocols. Our products undergo rigorous identity, purity, and impurity profile testing using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.