Description

1,2-Dihexadecanoyl-Rac-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine (PC) with two identical palmitoyl (C16:0) fatty acid chains. This compound is a critical building block for creating biomimetic membranes and liposomal delivery systems, offering superior consistency and batch-to-batch reproducibility essential for research and development. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications ranging from drug delivery to membrane biophysics.

Application

• Liposome & Nanoparticle Formulation: A key component for constructing unilamellar and multilamellar vesicles used in drug delivery systems for targeted therapy.
• Biomembrane Research: Used to create model lipid bilayers (e.g., supported lipid bilayers, black lipid membranes) for studying membrane protein interactions, permeability, and cell signaling.
• Cell Culture & Transfection Reagents: Serves as a raw material in the production of lipid-based transfection agents for introducing nucleic acids into cells.
• Diagnostic Assays: Employed in the development of diagnostic kits and sensors that utilize lipid membrane platforms.
• Cosmetic & Dermal Formulations: Used in high-end cosmetic products as a skin-identical lipid to enhance skin barrier function and delivery of active ingredients.
• Biophysical Studies: Essential for calorimetry (DSC), spectroscopy, and microscopy studies to understand lipid phase behavior and dynamics.

Basic Information

Product Name	1,2-Dihexadecanoyl-Rac-Glycero-3-Phosphocholine
CAS No.	2644-64-6
Molecular Formula	C40H80NO8P
Molecular Weight	734.04 g/mol
Synonyms	DPPC (Dipalmitoylphosphatidylcholine); 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (racemic); 1,2-Dipalmitoylphosphatidylcholine; Dipalmitoyl PC; 3-sn-Phosphatidylcholine, 1,2-dihexadecanoyl-; (Rac)-1,2-Dipalmitoylphosphatidylcholine; L-α-Phosphatidylcholine, dipalmitoyl (racemic); PC(16:0/16:0)
EINECS	220-161-8

Quality Control

Our 1,2-Dihexadecanoyl-Rac-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive research and GMP-guided formulation work. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. For long-term storage, desiccate at -20°C. The material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Phase Transition Temperature (Tm)	Approx. 41°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.