Description

Nicotine Bi-L-(+)-Tartrate is the tartrate salt form of the naturally occurring alkaloid nicotine, specifically the L-(+)-isomer. This high-purity salt form offers enhanced stability and precise dosing for advanced research and pharmaceutical development. It is a critical intermediate and reference standard for laboratories and manufacturers in the pharmaceutical, agrochemical, and life science sectors requiring a defined and consistent source of nicotine.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of nicotine-based therapeutics and as a certified reference standard for analytical method development and validation.
• Agrochemical Formulations: Used in the development of next-generation, targeted botanical insecticides and pest control agents.
• Neuroscience & Behavioral Studies: Serves as a precise pharmacological tool for studying nicotinic acetylcholine receptors (nAChRs) in academic and industrial research settings.
• Analytical Chemistry: Employed as a primary standard for calibrating equipment (e.g., HPLC, GC-MS) and ensuring accuracy in nicotine quantification across various matrices.
• Biochemical Reagent: Used in enzymatic assays and other biochemical studies where a pure, water-soluble form of nicotine is required.
• Electronic Cigarette & Nicotine Replacement Therapy (NRT) R&D: Provides a standardized raw material for the development and quality control of advanced nicotine delivery systems.

Basic Information

Product Name	Nicotine Bi-L-(+)-Tartrate
CAS No.	2624-48-8
Molecular Formula	C10H14N2 · 2C4H6O6
Molecular Weight	462.42 g/mol
Synonyms	(-)-Nicotine Bitartrate; L-Nicotine Bitartrate; Nicotine Hydrogen Tartrate; Nicotine Tartrate; (S)-Nicotine Bitartrate; 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate; Nicotine Di-L-tartrate; Nicotine Acid Tartrate
EINECS	220-097-1

Quality Control

Our Nicotine Bi-L-(+)-Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Chiral Purity ([α]D)	≥ 99.0% L-isomer
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.